分子量:38.4 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human GPD1, His Tag by the LAL method.

Buffer:50 mM Tris,150 mM NaCl,pH8.0

生物活性:

产品特性:Human GPD1, His Tag is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 38.4 kDa. The predicted N-terminus is Met. The reducing (R) protein migrates as 34 kDa in SDS-PAGE .

产品背景:Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD1), a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family, is also known as GPD-C or GPDH-C. The function of GPD1 is inhibited by zinc ions and sulfate. GPD1 can also interact selectively and non-covalently with nicotinamide adenine dinucleotide (NAD), a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. Mutations in GPD1 gene are a cause of Hypertriglyceridemia, transient infantile (HTGIT).